Po-Hao Chen, MD MBA



As Chief Informatics Officer at Cleveland Clinic Imaging Institute, I work alongside a team of 60 imaging informatics professionals. In this role, I manage a portfolio of radiology applications valuated at over $10M yearly. Recently, the team deployed a new Picture Archive and Communication System (PACS) over 300 radiologists nationwide serving 3 million imaging exams yearly.

Jointly appointed as Section Head of Clinical Informatics, I work with a team of physician-informaticists to integrate new technology into our radiology practice. One of our main projects is an "actionable results module," which tracks the imaging findings of over 100,000 patients.

In the area of imaging artificial intelligence (AI), I lead Cleveland Clinic's Imaging Data Science Center, introducing foundational tools like a high throughput data extraction and deidentification pipeline, full-text report search engine, and buidling a clinical AI workflow engine for radiology. With the Clinical Informatics section, we also brought several AI solutions to clinical practice, including tools in neuroradiology, breast imaging, thoracic radiology, and cardiovascular imaging.

In response to a cybersecurity breach in 2019, I led the transition of a local hospital to an analog workflow and the ensuing development of operational recovery plans for over 25 imaging locations in the Cleveland Clinic catchment. We set up a Cyber Attack Response Task Force to respond more quickly to future incidents.

As a clinical radiologist, my expertise is in musculoskeletal imaging, performing image-guided biopsies, joint injections, as well as a variety of diagnostic work in XR, CT, and MRI. I hold a board certification in both diagnostic radiology and nuclear medicine.

In the field of research, I have focused on the application of AI and advanced imaging techniques as an Assistant Professor at Cleveland Clinic Lerner College of Medicine. My work includes research in musculoskeletal, cardiovascular, and oncologic imaging as co-investigator or principal investigator in projects totaling approximately $5.4M of grant funding.

I am active in professional societies, contributing to the development of the Informatics e-Learning Hub with the ACR Commission for Informatics, chairing the ACR Informatics Advisory Council and ACR's annual Data Science Summit, and leading the RSNA's Informatics Policy Committee. For SIIM, I chair the Security Subcommittee to bring awareness and resilience to enterprise radiology operations.

As a dedicated clinical radiologist and informaticist, I harbor a deep passion for optimizing workflow, reducing burnout, and enhancing patient care through the strategic use of innovative technology. Guided by this passion, I actively engage in creating and implementing sophisticated digital solutions, recognizing that our ability to provide exceptional care is intrinsically tied to the efficiency and effectiveness of our technological systems.

You can find my profile on Twitter, LinkedIn, or follow the blog Figure Stuff Out. I enjoy imaging informatics, healthcare innovation, and good comfort food. The content of this website and the blog are of my personal opinion and do not represent the view of Cleveland Clinic.

View curriculum vitae

Research Projects

Natural Language Processing for Imaging Protocols

  • Presented at SIIM 2020 and published in Journal of Digital Imaging in 2022.
  • Won New Investigator Award
  • Protocols are "instruction sets" for radiology modalities. Proper protocol assignment is time consuming, but wrong protocols cause delayed care or incorrect care.
  • Comparing commercial auto ML builders (Google AutoML), with models using random forest, boosted trees, and deep learning approaches (e.g. ULMFiT).
  • AI for Acute Aortic Syndrome Detection

  • Algorithm combines deep learning, physics, and expert insight to expedite high accuracy detection of aortic dissection detection on chest CTA.
  • Patent-pending.
  • Acute aortic syndrome has 1-3% mortality per hour over the first 24 hours. Prompt detection saves lives.
  • Integration with radiology PACS and RIS for workflow enhancement.
  • Integrated Workflow Peer Learning Case Submission

  • Collaboration with Cleveland Clinic Imaging Quality. Presenting at SIIM 2020.
  • Peer Learning is the new form of Peer Review - Higher specificity for learning opportunities. Allow people to submit best cases in a nonthreatening way.
  • Voluntary case submission is the biggest problem.
  • Created a plugin for the PACS viewer - integrated case submission workflow without interruption and with auto-population of MRN and Accession.
  • Demonstrates substantially increased submission rates relative to old workflow
  • ARIES - Deep Learning + Bayesian System for Radiology Education and Dx Support

  • Plug-and-play Bayesian "artificial intelligence" for diagnostic support and education, with real-time update of differential diagnoses.
  • Approach validated in 2021 article as a high accuracy, explanable system for education.
  • Various features presented at 2016 SPIE Medical Imaging and 2018 SPIE Medical Imaging conferences
  • Educational mode presented at 2016 RSNA annual conference
  • Contributed to Bayes net research leading to additional oral presentations at ASNR, ACR, and SIIM.
  • Supported in part by an RSNA Educational grant with open-source release. Not a commercial product
  • RadCare - Resident-Led Radiology Consultation for General Medicine Wards

  • Created in-person consultation service for radiology residents to integrate with general medicine teams as part of normal radiology rotation.
  • Published in 2019 JACR article
  • 43% of all consultations led to a change in immediate clinical management decisions.
  • Radiology residents were shown to be no less productive while on consultation compared to in reading room.
  • 2017 AUR Research Scholars award for oral presentation.
  • Capricorn - Radiology Residency Analytics Tool

  • Residents: Track cases automatically for ACGME and MQSA. Discover discrepancies. Review attending changes to preliminary report. Crowdsource teaching files. (website)
  • Program Director: Curate resident performance dashboards. Identify great calls. Recognize underperformers.
  • Decreased missed PE on CTA by trainees using data-driven integrated quality improvement initiative
  • 2 peer-reviewed manuscripts on usability and on statistical analysis of attending variability.
  • RSNA oral presentations on analytics and approach to crowd-sourcing teaching files.
  • Winner of the 2014 Open Source Leadership Award at SIIM. Not a commercial product.
  • Centaur - Rapid-Fire Learning Module for Basic Imaging Findings

  • Radiology education tool. Single player "video game"-like mechanics. Rapid fire cases. Instant feedback. (website)
  • Trains perception of normal versus abnormal features.
  • 2 oral presentations at the RSNA conference.
  • Peer-reviewed manuscript showing improved trainee ability to perceive abnormality after one 20-minute session.
  • Integrating natural language processing and machine learning algorithms to categorize oncologic response in radiology reports

  • Created 9400 manually curated reports using structured reporting system "Code Oncology."
  • Studied the effect of NLP techniques (filter-based feature selection, N-gram tokenization, stop-word removal, word stemming, and tokenization models such as TF-IDF) on classification accuracy.
  • Compared performance of multiple machine learning algorithms on predictive accuracy.
  • Peer-reviewed manuscript published.
  • Unsupervised genomic and epigenetic analysis

  • Developed new techniques for probabilistic modeling of epigenetic relationships between miRNA, mRNA, and DNA polymorphism using differences between patient samples to bypass need for a priori data annotation.
  • Predictions validated by biochemical bench analysis.
  • Technique utilized in manuscripts published Science, Cell, Molecular Cell, and BMC Genomics.
  • Select Publications

    Curriculum Vitae

    1. Xavier BA, Chen PH. Natural Language Processing for Imaging Protocol Assignment: Machine Learning for Multiclass Classification of Abdominal CT Protocols Using Indication Text Data. J Digit Imaging [ePub ahead of print]. 2022 Jun 2
    2. Chen P-H, Bodak R, Gandhi NS. Ransomware Recovery and Imaging Operations: Lessons Learned and Planning Considerations. J Digit Imaging. 2021 Jun;34(3):731-740.
    3. Rudie JD, Duda J, Duong MT, Chen PH, Xie L, Kurtz R, et al. Brain MRI Deep Learning and Bayesian Inference System Augments Radiology Resident Performance. J Digit Imaging.s 2021 Aug;34(4):104958.
    4. Shah C, Kohlmyer S, Hunter K, Jones SE, Chen P-H. A translational clinical assessment workflow for the validation of external artificial intelligence models. In: Park BJ, Deserno TM, editors. Medical Imaging 2021: Imaging Informatics for Healthcare, Research, and Applications. Online Only, United States: SPIE; 2021. p. 14.
    5. Martin-Carreras TT, Li H, Chen P-H. Interpretative applications of artificial intelligence in musculoskeletal imaging: concepts, current practice, and future directions. J Med Artif Intell. 2020 Sep;3:1313.
    6. Shah C, Cook TS, Chen P-H, Hyland S, Heavener R, Kahn CE, et al. Improving Triage of After-Hours Radiology Examinations Through Worklist Unification. J Am Coll Radiol. 2020 Mar;S1546144020301459.
    7. Martin-Carreras T, Chen P-H. From Data to Value: How Artificial Intelligence Augments the Radiology Business to Create Value. Sem Musc Radiol. 2020 Feb;24(01):6573.
    8. Chen P-H. Essential Elements of Natural Language Processing: What the Radiologist Should Know. Acad Radiol. 2020 Jan;27(1):612.
    9. Duong MT, Rauschecker AM, Rudie JD, Chen P-H, Cook TS, Bryan RN, et al. Artificial intelligence for precision education in radiology. Br J Radiol. 2019 Jul 26;20190389.
    10. Gillman J, Wu SE, Rowland J, Scanlon M, Chen P-H. Comparison of In-Person and Digital Radiology Resident Consultation Services. J Am Coll Radiol. 2019 Feb 4; S1546144018314856
    11. Chen P-H, Scanlon MH. Teaching Radiology Trainees from the Perspective of a Millennial. Academic Radiology. 2018 Jun;25(6):794-800.
    12. Chen P-H, Cross N. IoT in Radiology: Using Raspberry Pi to Automatically Log Telephone Calls in the Reading Room. Journal of Digital Imaging. 2018 Jun;31(3):371-8.
    13. Deitte LA, Chen P-H, Scanlon MH, Heitkamp DE, Davis LP, Urban S, et al. Twenty-four-Seven In-house Faculty and Resident Education. Journal of the American College of Radiology. 2018 Jan;15(1):90a.
    14. Chen P-H, Zafar H, Galperin-Aizenberg M, Cook T. Integrating Natural Language Processing and Machine Learning Algorithms to Categorize Oncologic Response in Radiology Reports. J Digit Imaging. 2018 Apr;31(2):17884.

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